Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Decarboxylation Reactions. II. Reaction of Conjugated Unsaturated Ketones and Nitriles with Carboxylic Acids
藤井 真寺尾 良保関屋 実
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ジャーナル フリー

1974 年 22 巻 11 号 p. 2675-2679

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The present paper discloses a decarboxylation reaction of several conjugated unsaturated ketones and nitriles with carboxylic acids such as acetoacetic acid, malonic acid and cyanoacetic acid. In the reaction these carboxylic acids are decarboxylated and introduced at β-carbon of the conjugated unsaturated compounds. Thus there have been provided a effective means of introducing acetonyl, carboxymethyl and cyanomethyl at that position.

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© The Pharmaceutical Society of Japan
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