Abstract
Preliminary investigations on the interaction between diethyl phosphorazidate and benzoic acid revealed that phosphoryl azides may be a convenient reagent for a modified Curtius reaction and the amide bond formation. Among phosphoryl azides, diphenyl phosphorazidate (DPPA) which was easily prepared by the action of sodium azide on diphenyl phosphorochloridate was chosen for the investigation on the racemization-free peptide synthesis. The Young test under various conditions proved that DPPA may be a new convenient reagent for the racemization-free peptide synthesis. The results are summarized in Tables.
