Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isolation and Characterization of Biliary Metabolites of Estriol in the Rat
TOSHIO NAMBARA, JUNZO ISHIGURO, YOSHIHIKO KAWARADA, HIDEO TAJIMA
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1974 Volume 22 Issue 4 Pages 889-893

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Abstract
16-Oxoestradiol (IV), two pairs of isomeric 2-and 3-methyl ethers of 2-hydroxyestriol (II, III) and 2-hydroxy-16-oxoestradiol (V, VI) have been characterized as biliary glucuronide metabolites of estriol in the rat. This is the first report on in vivo formation of catechol estrogen having the 16-oxo-17β-ol structure.
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© The Pharmaceutical Society of Japan
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