Amino Acids and Peptides. XII. Phosphorus in Organic Synthesis. VIII. Reaction of Malonic Acid Half Esters with Diphenyl Phosphorazidate
1974 年 22 巻 6 号 p. 1398-1404
詳細
1974 年 22 巻 6 号 p. 1398-1404
Application of the modified Curtius reaction by DPPA to some malonic acid half esters revealed that esterification occurred in a one-step process but the rearrangement reaction took place in a two-in-one-reaction procedure, the results of which are summarized in Tables I and II. The latter procedure may provide a new simple method for the synthesis of α-amino acids.
