Alkylation of Phthalimidines

YOSHIYASU TERAO; MINORU SEKIYA

doi:10.1248/cpb.23.184

Abstract

The present paper provides a new useful means of synthesis of 2, 3, 3-trisubstituted phthalimidines. Alkylation of phthalimidines at 3-position has been found to proceed with alkyl halide in liquid ammonia in the presence of potassium amide.

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