2-Substituted Thiazolines. III. : Reaction with N-Benzoyl-α-amino Acids

Abstract

2-Ethylthiothiazoline was reacted with N-benzoyl-α-amino acids in acetic anhydride to give I. Ia was converted into II, III, IV, and V. The oxazolone ring of Ib and Ic was opened to give XI. XIb was converted into thiazoline (XII) and XIII. These thiazolines were reduced to thiazolidine (XIV) and XV, and then converted into the respective aldehydes, XVI and XVII.