抄録
Quinoline 1-oxide (Ia) reacted with potassium cyanate and tosyl chloride in ethanol at -10°to give ethyl N-(2-quinolyl) carbamate (IIa) in 70% yield. The reaction under reflux caused decrease of the yield of Ia (11%) and additional formation of 2-ethoxyquinoline (IIIa) (54%) and carbostyril (IV) (29%). Unless ethanol was used, no definite product was isolated. Reactions of some derivatives of Ia as well as that of isoquinoline 2-oxide were also examined under the same conditions.
