Abstract
3, 4-Dimethoxyphenethyl hydrazine (III), reacting with ethyl γ-oxopimelate, was converted into the hydrazone (IV), which was reduced to the corresponding hydrazine (V). V was then subjected to the intramolecular ring closure to afford (VI), which showed dimorphism. VI was subjected to the Bischler-Napieralski reaction accompanied with the reduction to afford the titled compound (VIII), which was also obtained by the Bischler-Napieralski ring closure of V followed by the reduction and the ring closure to furnish the D-ring of the diazasteroid. The stereochemistry of VIII was discussed based on its nuclear magnetic resonance data and its mercuric acetate oxidation.
