Studies on 1-Alkyl-2 (1H)-pyridone Derivatives. XXIV. The Friedel-Crafts Reaction of 1-Methyl-2 (1H)-pyridone and Its Derivatives with Acid Anhydride

Abstract

The Friedel-Crafts reactions of 1-methyl-2 (1H)-pyridone (I), 2-methyl-1 (2H)-isoquinolone (II), and 1-methyl-2 (1H)-quinolone (III) with acid anhydride, principally benzoic anhydride, were carried out. In the case of I and II, reaction with acid anhydride gave the products in a good yield, but in the case of III, the reaction with acid anhydride gave products in much less yield than that with acid chloride.