Abstract
The reaction of acetoneberberine (I) with methyl iodide was found to give 8, 13a-(2'-oxopropano)-13, 13-dimethylberbine derivative (IV) and 8, 13a-(2'-oxopropano)-13-methylberbine derivative (V) as side products together with the expected 13-methyl-berberinium (II) and berberinium iodide (III). Analogous reaction of I with allyl bromide gave rise to 8, 13a-(2'-oxopropano)-13, 13-diallylberbine derivative (XI). The structures of products were deduced from chemical and spectral data.
