Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Unusual Reaction of 3-Chloro-3-nitroalkylindolin-2-ones
HIROTAKA OTOMASUKEI YOSHIDAKYUJI NATORI
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1975 Volume 23 Issue 7 Pages 1436-1439

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Abstract
The reaction of 3-chloro-3-nitromethylindolin-2-one (2a) with aniline resulted the formation of 3-anilinomethylene-(4a) and 3-(p-phenylazo) anilinomethyleneindolin-2-one (5). Chromatographying of 2a, b using Al2O2 in chloroform solution gave 3-nitro-methyleneindolin-2-ones (7a, b), which were also reacted with amines to give 3-amino-methyleneindolin-2-ones (4a, b and 8a, b).
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© The Pharmaceutical Society of Japan
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