Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Model Studies on Percutaneous Absorption and Transport in the Ointment. I. Theoretical Aspects
KAYOKO KAKEMIHARUKO KAMEDAMASAWO KAKEMIMICHIHIRO UEDATAMOTSU KOIZUMI
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1975 Volume 23 Issue 9 Pages 2109-2113

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Abstract
Mathematical models were defined that simulate the percutaneous absorption of drug and its transport in the ointment. Ointment and skin were, respectively, assumed as homogeneous phases through which drug diffuses according to Fick's law. Blood compartment and drug disposition were also taken into account.
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© The Pharmaceutical Society of Japan
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