Synthesis of 7α-Methoxy-7-[2-(substituted thio) acetamido] cephalosporin Derivatives and Their Antibacterial Activities

抄録

The synthesis of new 7α-methoxy-7-(2-substituted thio) acetamido derivatives of cephalosporin by nucleophilic displacement of the halogen atom of 7β-(2-halogenoacetamido)-7-methoxy cephalosporanic acid derivatives was described. The in vitro antimicrobial activities were also described.