Isolation of New C₂₆ Bile Alcohols from Bullfrog Bile

Abstract

The bile alcohol constituents of bullfrog were examined to give four new C₂₆ bile alcohols along with three known bile alcohols, 5α-cyprinol, 5α-ranol, and 5β-ranol. On the basis of the spectral data and the direct comparison with synthetic samples, the structures of the new bile alcohols were established to be four 27-norcholestane-3α, 7α, 12α, 24-tetrols isomeric at C-5 and C-24, (I), (III), (VII), and (VIII).