Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of N-Haloamide. XXVII. Reaction of N, N-Dihaloamides with Dienes
山崎 明美寺内 弘実竹村 庄司
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ジャーナル フリー

1976 年 24 巻 11 号 p. 2841-2849

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The reaction of N, N-dibromo-, and dichlorobenzenesulfonamides (DBBS and DCBS) and N, N-dichlorourethan (DCU) with dienes were examined. Reactions of DBBS or DCBS with 1, 5-hexadiene, 1, 4-pentadiene, and 1, 4-diphenyl-1, 3-butadiene caused cyclic additions to give pyrrolidine derivatives in some extent accompanying with open-chain adducts whereas DCU gave no cyclic adduct but only mixtures of open chain-adducts. The reactions of N, N-dihaloamides with 1, 4-cyclohexadiene also gave acyclic adducts.
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© The Pharmaceutical Society of Japan
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