Identification of a Novel Aminonucleoside Produced by Enterobacter sp. as 2'-Amino-2'-deoxyguanosine

抄録

A novel guanosine analog, aminonucleoside antibiotics (2AG), produced by Enterobacter sp., was identified as 9-(2'-amino-2'-deoxy-β-D-ribofuranosyl)-guanine (2'-amino-2'-deoxyguanosine) by proton magnetic resonance and carbon-13 nuclear magnetic resonance spectra of 2AG and acetylated 2AG, and also by the comparison of the aminosugar obtained by hydrolysis of 2AG with 2-amino-2-deoxypentoses appeared in the literatures. This is the first report on the occurrence of 2-amino-2-deoxy-D-ribose in nature.