Abstract
Effect of stannous chloride on the urinary calcium concentration was examined in rats intraperitoneally administered with stannous chloride. The concentration of calcium in urine was significantly decreased by the administration of stannous chloride (Sn 3.0 mg/100 g), while the concentration of inorganic phosphorus was not altered markedly. The reduction of calcium concentration in the urine, induced by stannous chloride, was not restored by the injection of calcium in rats treated with stannous chloride. The present study indicates that the administration of stannous chloride inhibited the excretion of calcium into urine of rats.