Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
Pericarp Saponins of Akebia quinata DECNE. I. Glycosides of Hederagenin and Oleanolic Acid
RYUICHI HIGUCHITOSHIO KAWASAKI
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1976 Volume 24 Issue 5 Pages 1021-1032

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Abstract

Two free triterpenoids and twelve triterpenoid saponins were isolated from the fresh pericarps of Akebia quinata DECNE. (Lardizabalaceae). Ten saponins, PA-G, PJ2, PJ3 and PK, of the above twelve were characterized as follows : PA (I), hederagenin (hederag.) 3-O-α-L-ara·pyranoside ; PF (II), hederag. 3-O-β-D-glc·pyr-(1→2)-α-L-ara·pyranoside ; PB (III), oleanolic acid (ol. acid) 3-O-α-L-rha·pyr-(1→2)-α-L-ara·pyranoside ; Pc (VI), hederag. 3-O-β-D-xyl·pyr-(1→3)-α-L-ara·pyranoside ; PD (IX), hederag. 3-O-α-L-rha·pyr-(1→2)-α-L-ara·pyranoside ; PE (XI), ol, acid 3-O-β-D-glc·pyr-(1→2)-α-L-ara·pyranoside ; PG (XIII), hederag. 3-O-β-D-xyl·pyr-(1→3)-α-L-rha·pyr-(1→2)-α-L-ara·pyranoside ; PJz (XV') 3-O-α-L-ara·pyranosyl-hederag. 28-O-α-L-rha·pyr-(1→4)-β-D-glc·pyr-(1→6)-β-D-glc·pyranoside ; PJs (XIX'), 3-O-α-L-rha·pyr-(1→2)-α-L-ara·pyranosyl-ol. acid 28-O-α-L-rha·pyr-(1→4)-β-D-glc·pyr-(1→6)-β-D-glc·pyranoside ; PK (XXI), 3-O-α-L-rha·pyr-(1→2)-α-L-ara·pyranosyl-hederag. 28-O-α-L-rha·pyr-(1→4)-β-D-glc·pyr-(1→6)-β-D-glc·pyranoside. VI, XI and XV'are new members of the group of hederagenin and oleanolic acid oligoglycosides. It is noted that they all have the common unit, 3-O-α-L-ara·pyranoside, and that XV', XIX'and XX, having the same trisaccharide combined with the 28-carboxyl group of the aglycone, are corresponding to I, III and IX, respectively.

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