Reaction of sec-Amides with Metal Hydrides. I. A Combination of Sodium Borohydride with Anilides as a Novel Reducing Reagent for Carbonyl Compounds

Abstract

Sodium anilidoborohydrides were synthesized from sodium borohydride and anilides in pyridine or in α-picoline, and these compounds were found to be useful reagents for facile reduction of both esters in α-picoline and aldehydes or ketones in dichloromethane. The structure of sodium acetanilidoborohydride was discussed.