Reactions of Cyclic-enaminoketones with Diacylethylenes. Regioselective Synthesis of 4-Oxotetrahydroindole, 5-Oxotetrahydroquinoline, Pyrrolo- and Pyrido [2, 3-d] pyrimidines

Abstract

A study has been made of the reaction of 3-aminocyclohex-2-enones and 6-amino-1, 3-dimethyluracil with diacylethylene. By the selection of reaction conditions either 4-oxotetrahydroindole or 5-oxotetrahydroquinoline derivatives from 3-aminocyclohex-2-enones and either pyrrolo- or pyrido [2, 3-d] pyrimidine derivatives from 6-amino-1, 3-dimethyluracil were obtained in fairly high yields, respectively.