Reactivity of 2, 4 (5)-Dialkylimidazoles. Synthesis of 6, 7, 8, 9-Tetrahydro-5H-imidazo [1, 5-a] [1, 4] diazepine Derivatives

Abstract

6, 7, 8, 9-Tetrahydro-5H-imidazo [1, 5-a] [1, 4] diazepine derivatives (IV) were synthesized by the reaction of formalin with 1-γ-aminopropylimidazole derivatives (III) prepared by cyanoethylation and then catalytic hydrogenation of the imidazole derivatives (I).