Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Metabolic Products of Aspergillus terreus. I. Metabolites of the Strain IFO 6123
山本 譲西村 憲一桐山 典城
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1976 年 24 巻 8 号 p. 1853-1859

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The metabolites of Aspergillus terreus IFO 6123 were studied. 3-Methylorsellinic acid, 4-O-demethylbarbatic acid and a new metabolite named asterriquinone were isolated. The chemical structure of asterriquinone was established as 2, 5-bis-[N-(1", 1"-dimethyl-2"-propenyl)-indoyl-3']-3, 6-dihydroxy-1, 4-benzoquinone by chemical and physical experimental data. The incorporation experiments using 14C-labeled compounds showed that asterriquinone is biosynthesized from tryptophan and isopentenyl unit derived from mevalonate.
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© The Pharmaceutical Society of Japan
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