Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reaction of Schiff Bases with Trichloroacetyl Chloride in the Presence of Triphenylphosphine
森本 俊明関屋 実
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1976 年 24 巻 8 号 p. 1935-1938

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It has now been found that trichloroacetyl chloride is capable to react with Schiff bases in the presence of triphenylphosphine to give 3, 3-dichloro-2-azetidinones. Mechanistically the reaction appears to involve the chlorine cation extraction from the initially formed adduct by triphenylphosphine.

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© The Pharmaceutical Society of Japan
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