Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Arylindoles. I. Synthesis of Some N-Arylindoles
MISBAHUL AIN KHANEMELY KAZAN ROCHA
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1977 Volume 25 Issue 11 Pages 3110-3114

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Abstract
Indole, 2-phenylindole, indole-2-carboxylic acid, indole-3-carboxaldehyde, 3-acetylindole and gramine were condensed with bromobenzene and halonitrobenzenes under the Ullmann conditions (copper (II) oxide catalyst and N, N-dimethylformamide as the solvent). The corresponding N-arylindoles were isolated in good yields with the exception of the gramine due to its possible decomposition under these reaction conditions. Spectral data (infrared and proton magnetic resonance) for the new compounds is presented.
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© The Pharmaceutical Society of Japan
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