Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Preparation of Ethylcellulose Microcapsules containing Magnesium Aluminum Hydroxide Hydrate
SYUICHI KASAIMASUMI KOISHI
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Keywords: wall thickness
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1977 Volume 25 Issue 2 Pages 314-320

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Abstract
Ethylcellulose microcapsules containing magnesium aluminum hydroxide hydrate were prepared by the phase separation method using organic polymer solutions and observation on the formation mechanism of wall film during the microencapsulation process was done. The system of ethylcellulose-dichloromethane-n-hexane was used for microencapsulation. In this system, it was found that coacervate drops deposited first on the hydrophobic surface of the core material and the wall was then formed. Furthermore, the region of constant wall thickness was observed irrespective of the weight of ethylcellulose in the microcapsules finally obtained.
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© The Pharmaceutical Society of Japan
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