Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Antitumor Activity of 4-Nitropyridazine 1-Oxides and Related Compounds for AH-13
神谷 庄造安斉 美知子中島 利章末吉 祥子丹野 雅幸鈴木 郁生石舘 基小田嶋 成和
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1977 年 25 巻 3 号 p. 504-506

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Antitumor activity of 4-nitropyridazine 1-oxides and related compounds was tested with AH-13 system. Among these nitro compounds, 3, 6-dimethoxy-4-nitropyridazine 1-oxide (III) and 4-nitrocinnoline 1-oxide (XIII) were the most effective. 4-Nitropyridazine 1-oxide (I), 3, 6-dimethyl-4-nitropyridazine 1-oxide (II) and 3-alkoxy-4-nitro-6-chloropyridazine 1-oxides (VI, VII) were effective to some extent.
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© The Pharmaceutical Society of Japan
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