Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Pharmacological Studies of Panacis Japonici Rhizoma. I
HIROSHI SAITOYIENMEI LEEKEIJIRO TAKAGISHOJI SHIBATAJUNZO SHOJINORIKO KONDO
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Keywords: Panax Ginseng root
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1977 Volume 25 Issue 5 Pages 1017-1025

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Abstract

Pharmacological properties of preparations from Panacis Japonici Rhizoma were studied by the screening methods consisting of 5 tests. CNS-depressant, tranquillizing, cholinergic, anticholinergic, histamine-like, antihistamine-like, antinicotinic, blood pressure elevating and lowering, and antiinflammatory activities were estimated. Chikusetsusaponin III whose aglycone is 20S-protopanaxadiol is especially remarkable as it has tranquillizing, anticholinergic, antihistamine-like, antinicotinic, and blood pressure elevating and lowering activities. Cholinergic, histamine-like and blood pressure elevating activities were found in the fraction which did not contain saponins. Antiinflammatory activity was estimated to chikesetsusaponin V.

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© The Pharmaceutical Society of Japan
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