Abstract
In the suspension cultures using callus induced from Cannabis sativa L., geraniol, nerol, olivetol and ethyl olivetolate which are cannabinoid precursors were not biotransformed to cannabinoids. We found that primary and secondary allylic alcohols such as geraniol, nerol, trans-cinnamyl alcohol, isophorol and trans-verbenol were biotransformed to the corresponding aldehydes. On the other hand, acyclic secondary allylic alcohols such as α-ionol, β-ionol and 4-phenyl-3-buten-2-ol were not biotransformed. Further, we clarified that the enzyme which catalyzed the oxidation of allylic alcohols was an alcohol oxidase.
