Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Biotransformation of Cannabinoid Precursors and Related Alcohols by Suspension Cultures of Callus induced from Cannabis sativa L.
糸川 秀治竹谷 孝一三橋 進
著者情報
キーワード: alcohol oxidase
ジャーナル フリー

1977 年 25 巻 8 号 p. 1941-1946

詳細
抄録
In the suspension cultures using callus induced from Cannabis sativa L., geraniol, nerol, olivetol and ethyl olivetolate which are cannabinoid precursors were not biotransformed to cannabinoids. We found that primary and secondary allylic alcohols such as geraniol, nerol, trans-cinnamyl alcohol, isophorol and trans-verbenol were biotransformed to the corresponding aldehydes. On the other hand, acyclic secondary allylic alcohols such as α-ionol, β-ionol and 4-phenyl-3-buten-2-ol were not biotransformed. Further, we clarified that the enzyme which catalyzed the oxidation of allylic alcohols was an alcohol oxidase.
著者関連情報
© The Pharmaceutical Society of Japan
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