Disodium N-(2-Carboxyphenyl)-4-chloroanthranilate : Enhancement of Immune Response in Mice

YOSHIYUKI OHSUGI; TOSHIAKI NAKANO; SHUNICHI HATA; TAKASHI MATSUNO; YASUHO NISHII; YOSHIO TAKAGAKI

doi:10.1248/cpb.25.2143

YOSHIYUKI OHSUGI, TOSHIAKI NAKANO, SHUNICHI HATA, TAKASHI MATSUNO, YASUHO NISHII, YOSHIO TAKAGAKI

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Keywords: bacterial lipopolysaccharide

JOURNAL FREE ACCESS

1977 Volume 25 Issue 8 Pages 2143-2145

DOI https://doi.org/10.1248/cpb.25.2143

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Abstract

Effects of disodium N-(2-carboxyphenyl)-4-chloroanthranilate, which was newly synthesized, on the immune response in mice were investigated. An oral administration of this compound increased the production of splenic plaque forming cells against both a thymus-dependent (sheep red blood cells) and a thymus-independent antigen (bacterial lipopolysaccharide).

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