Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of D-Glucuronic Acid Derivatives of 5-Fluorouracil having O-Glycosidic Linkage
金子 正勝田中 宏幸木村 美佐子清水 文治
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1977 年 25 巻 9 号 p. 2458-2460

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5-Fluorouracil-4-O-glucuronic acid derivatives (V, VII) were synthesized by a condensation reaction of the silver salt of 2-benzyloxy-5-fluoro-4-pyrimidone with methyl 1-bromo-1-deoxy-2, 3, 4-tri-O-acetyl-α-D-glucopyranuronate and subsequent careful removal of the protecting group.

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© The Pharmaceutical Society of Japan
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