Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of the Nonadecapeptide corresponding to Porcine δ-Endorphin
MINORU KUBOTATADAMASA HIRAYAMAOSAMU NAGASEHARUAKI YAJIMA
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Keywords: tail pinch method
JOURNAL FREE ACCESS

1978 Volume 26 Issue 12 Pages 3901-3904

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Abstract
The nonadecapeptide corresponding to δ-endorphin, a plasmin hydrolysate of porcine β-lipotropin, was synthesized using protecting groups removable by methanesulfonic acid. Analgesic activity of the synthetic peptide was estimated as active as Leu-enkephalin by the tail pinch method.
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© The Pharmaceutical Society of Japan
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