Studies on Heterocycles Carbon-13 Magnetic Resonance Spectroscopy. XI. Nitrogen Heterocycles. (1). 6-Substituted Quinoline and Quinoxaline Derivatives

Abstract

The assignment of ¹³C nuclear magnetic resonance chemical shifts of 6-substituted quinoline and quinoxaline series were confirmed, and the additivity rules of ¹³C chemical shifts of 2-substituted naphthalene derivatives were approved for both 6-substituted quinoline and quinoxaline derivatives. The correlation coefficient of meta-like position is promoted by the linear combination of chemical shifts at corresponding meta position of 2-substituted naphthalene derivatives and substituent constants σ_π.