Bicyclo [3. 3. 1] nonanes as Synthetic Intermediates. II. Synthesis of Bicyclo [3. n. 1] alkan-3-one via α, α'Annelation of Cycloalkanone

Abstract

Bicyclo [4. 3. 1] decan-8-one (3) was synthesized from 8-benzoylbicyclo [4. 3. 1] decan-10-one (4) by making use of regio-selective deketalization of a bisketal (8). Bicyclo-[3. 3. 1] nonan-3-one (1) and bicyclo [3. 2. 1] octan-3-one (2) were also prepared from the corresponding 3-benzoylbicyclo [3. n. 1] alkanone, but via a modified route.