Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Metalation of Alkylpyridazines. I. Alkylation of Metalated Alkylpyridazines with Alkyl Halides
AKIO OHSAWATOMIO UEZUHIROSHI IGETA
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1978 Volume 26 Issue 8 Pages 2428-2434

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Abstract
Side-chain lithiation with lithium diisopropylamide and subsequent alkylation of various alkylpyridazines have been investigated. The lithiated side chains of alkylpyridazines were alkylated efficiently with alkyl halides.
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© The Pharmaceutical Society of Japan
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