Major metabolites of the antianginal drug, Diltiazem, 3 (S)-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2(S)-(4-methoxyphenyl)-1, 5-benzothiazepin-4(5H)-one, have been synthesized. In connection with these metabolites, several S- and N-oxides were prepared.
