Formic Acid Reduction. XXVII. Selective Reduction of Carbon-Carbon Double Bonds conjugated with Nitro and Sulfonyl Groups

Abstract

Selective reduction of carbon-carbon double bond conjugated with nitro group has been demonstrated with a number of examples by the use of the TEAF reagent (triethylamine-formic acid azeotrope) in N, N-dimethylformamide. In addition, formic acid reduction of carbon-carbon double bond conjugated with both sulfonyl and other electron-withdrawing groups has been exemplified by the same manner.