Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Heterocycles. VII. Reaction of 12-Hydroxy-5-oxa-6-oxo-5, 6-dihydrochrysene with Methylamine
YOSHIHIRO HARIGAYATSUTOMU SUZUKIMASAYUKI ONDA
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1979 Volume 27 Issue 11 Pages 2636-2641

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Abstract

The lactone (5) reacts with methylamine to afford the methylaminophthalide (6). On the basis of the reactions of 6 and related compounds, the spiro lactam (14) is suggested to be an intermediate in the formation of 6 from 5.

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© The Pharmaceutical Society of Japan
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