Synthesis of 24, 24-Difluoro-1α, 25-dihydroxyvitamin D3
キーワード:
NMR spectra
1979 年 27 巻 12 号 p. 3196-3198
詳細
1979 年 27 巻 12 号 p. 3196-3198
24, 24-Difluoro-1α, 25-dihydroxyvitamin D3 (1) has been synthesized from 24, 24-difluoro-5β-cholestane-3α, 25-diol (2) as an antimetabolic analogue of 1α, 25-dihydroxyvitamin D3 to study the role of the 24-hydroxylation in the metabolism of vitamin D3.
