Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of 2-Amino-2-deoxy-β-D-arabinofuranosyl Nucleosides
佐藤 章今井 良二中溝 喜博平田 正
著者情報
キーワード: cytotoxic activity
ジャーナル フリー

1979 年 27 巻 3 号 p. 821-823

詳細
抄録
9-(2-Deoxy-2-amino-β-D-arabinofuranosyl) adenine (IIIa) and guanine (IIIb) were synthesized from the corresponding azide compounds (II) obtained by nucleophilic substitution of tosyloxy groups of 2'-O-p-toluensulfonyladenosine (Ia) and guanosine (Ib), respectively. Their antitumor activity against sarcoma-180 solid tumor and cytotoxic activity against HeLa-S3 cells were determined.
著者関連情報
© The Pharmaceutical Society of Japan
前の記事 次の記事
feedback
Top