Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Modification of α-Santonin. III. Synthesis of Dihydrocostunolide
YASUO FUJIMOTOTAKESHI SHIMIZUMASAYUKI OHMORITAKASHI TATSUNO
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1979 Volume 27 Issue 4 Pages 923-933

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Abstract
A new synthetic method for cyclodecanone intermediates (33 and 38) which are useful for the synthesis of not only germacranolide but guaianolide-type sesquiterpenoids is described. Synthesis of dihydrocostunolide, a typical germacranolide, is also described.
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© The Pharmaceutical Society of Japan
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