Synthesis of 4-Substituted 1, 2-Dihydropyridazino [3, 4-b] quinoxalines from 3-(N, N-Dimethylaminocarbonyl) furo [2, 3-b] quinoxaline

Abstract

4-Substituted 1, 2-dihydropyridazino [3, 4-b] quinoxalines (VII, VIIIa, and VIIIb) were synthesized from 3-(N, N-dimethylaminocarbonyl) furo [2, 3-b] quinoxaline hydrochloride (I) via 3-oxo-2-(2'H-pyrido [1', 2'-a] pyrimidin-2'-on-3'-yl)-3, 4-dihydroquinoxaline (III) and 3-chloro-2-(2'H-pyrido [1', 2'-a] pyrimidin-2'-on-3'-yl) quinoxaline (V).