Preparation of Specific Antibody to 2, 3-Trimethylene-4-quinazolone for the Immunoassay of Δ¹-Pyrroline

抄録

Anti-2, 3-trimethylene-4-quinazolone antibody was prepared from the sera of two rabbits immunized with an antigen which was a conjugate of 6-(β-carboxypropionyl)-amino-2, 3-trimethylene-4-quinazolone and bovine serum albumin in a molar ratio of approximately 20 to 1. Specific affinity of the antibody for 2, 3-trimethylene-4-quinazolone was confirmed by comparison of the affinities for thirteen structurally related compounds.