Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Formation of Pyrazole Derivatives from β-Substituted Pyridinium Salts
SHIGERU TANAKAKAZUYUKI WACHIATSUSUKE TERADA
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Keywords: reaction mechanism
JOURNAL FREE ACCESS

1980 Volume 28 Issue 4 Pages 1265-1269

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Abstract
Treatment of 1-methyl-3-phenylhydrazonomethyl pyridinium iodides (2a-f) with a base gave pyrazole derivatives (3 and 4) with expulsion of the pyridine ring. A possible mechanism for the formation of pyrazole derivatives id discussed.
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© The Pharmaceutical Society of Japan
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