Amino Acids and Peptides. V. Synthesis of N-L-and D-Alanyl-1-aminoethylphosphonic Acids

Abstract

N-L-Alanyl-1-aminoethylphosphonic acid (IIIa) and N-D-alanyl-1-aminoethylphos-phonic acid (IIIb) were synthesized. IIIb did not exhibit any antibacterial activity against gram-positive or gram-negative organisms, but IIIa showed antibacterial activity against some gram-negative organisms.