Abstract
Two prenylcoumarins, XII and XIII, were isolated from the root of Angelica pubescens MAXIM. (Umbelliferae) growing in Japan, together with eleven known coumarins, osthol (I), bergapten (II), glabra-lactone (III), angelol (IV), psoralen (V), xanthotoxin (VI), isopimpinellin (VII), byak-angelicin (VIII), coumurrayin (IX), 7-methoxy-8-senecioylcoumarin (X) and scopoletin (XI). The structures of XII and XIII were elucidated as 8-(3-hydroxyisovaleroyl)-5, 7-dimethoxycoumarin and 5-isopentenyloxy-7-methoxy-8-senecioylcoumarin, respectively, by chemical and spectral studies. XIII is a new natural prenylcoumarin, and was named angelin.
