Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Therapy for Urolithiasis with Hydroxamic Acids. I. Synthesis of New N-(Aroyl) glycinohydroxamic Acid Derivatives and Related Compounds
KEIICHI MUNAKATA, SATORU TANAKA, SHOJI TOYOSHIMA
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Keywords: Proteus mirabilis
JOURNAL FREE ACCESS

1980 Volume 28 Issue 7 Pages 2045-2051

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Abstract
With the aim of finding a therapeutic agent for urolithiasis, forty-three new N-(aroyl)-glycinohydroxamic acid derivatives and related compounds were synthesized and examined for urease inhibitory activity. Their urinary excretion in rats was also determined.
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© The Pharmaceutical Society of Japan
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