Comparative Studies on Two Active Enzyme Forms of Human Urinary Urokinase. II. pH- and Heat-stabilities of Plasminogen Activator Activity
キーワード:
gradient gel electrophoresis
1981 年 29 巻 2 号 p. 472-475
詳細
1981 年 29 巻 2 号 p. 472-475
pH-stability curves and heat inactivation of the MW 55000 form (H-UK) and MW 36000 form (L-UK) of human urinary urokinase [EC 3. 4. 21. 31] were investigated by measurements of plasminogen activator activity. L-UK was distinctly more stable than H-UK (in terms of activity) on incubation at pH 6.8-9.6 or on heat treatment at temperatures above 60°. The ranges of pH 8.2-9.0 and 5-37°, were favorable for both H-UK and L-UK.
