Identification of a Reactive Metabolite of the Mutagen, 2-Amino-3-methylimidazolo [4, 5-f] quinoline
キーワード:
DNA modification
1981 年 29 巻 2 号 p. 590-593
詳細
1981 年 29 巻 2 号 p. 590-593
A reactive major metabolite of the mutagen, 2-amino-3-methylimidazolo [4, 5-f]-quinoline (IQ), by rat liver microsomes was 2-hydroxyamino-3-methylimidazolo [4, 5-f]-quinoline (N-OH-IQ). The synthesis and reaction with DNA of N-OH-IQ were discussed.
