Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Reduction of 2, 2, 2-Trichloroethylamines with Lithium Aluminum Hydride
MASANORI TAKAMATSU, MINORU SEKIYA
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Keywords: ring expansion
JOURNAL FREE ACCESS

1981 Volume 29 Issue 3 Pages 616-622

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Abstract
It has been found that the lithium aluminum hydride reduction of 2, 2, 2-trichloroethylamines occurs to give amines with rearranged carbon skeletons or aziridines, depending on the precise substrate structure.
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© The Pharmaceutical Society of Japan
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